Students align pieces of rope or paper "DNA" based on the distance between "markers" to generate a DNA consensus sequence. The activity helps students see how fragments of tagged DNA can be used to make a physical map of a genome.Learning objectives
- To sequence or map long stretches of DNA, researchers first cut the DNA into shorter fragments, then piece them back together.
- Overlapping sequences or features on short segments of DNA can be used to assemble much longer contiguous DNA sequences, or “contigs.”
Connect-A-Contig paper version PDF