DNA & Histone Model
A 3-D cut-and-paste model depicting how histone, acetyl and methyl molecules control access to DNA and affect gene expression. Can be used as a companion to, or in place of, the Gene Control interactive.
Tip: With the epigenome-specific instructions and molecule models removed, these print-outs can be used to create general chromosome models. Modify the model further by copying the DNA strips (page 7) on to help model recombination (crossing over) during meiosis.Learning Objectives
- DNA is coiled around histones.
- Tightly coiled DNA is inaccessible to gene reading machinery.
- Methyl molecules bind to DNA and block access to genes.
- Acetyl molecules bind to histones and improve access to genes.